YK11 Capsules

YK-11 Myostine Capsules United States

YK-11 Myostine Capsules SARM is a synthetic steroid compound that researchers discovered in 2011. Japanese scientist Yuichiro Kanno published peer-reviewed studies on it in 2013. Unlike traditional SARMs, YK-11 also works as a potent myostatin inhibitor. This gives it the unique ability to increase muscle growth beyond that of typical SARMs. YK-11 is a research chemical for research purposes, and its safety and effectiveness are still unproven.

United States Researchers consider YK-11 a steroidal selective androgen receptor modulator. It binds to androgen receptors as a partial androgen receptor agonist. In this way, it activates anabolic factors in muscle tissue. These anabolic effects boost muscle development and may prevent muscle wasting.

As a myostatin inhibitor, YK-11 increases follistatin expression, which then blocks myostatin levels from exerting their full effect (it does not stop myostatin production). The muscle-building action of YK-11 Myostine Capsules comes from higher follistatin levels, produced by muscle cells. This expression lowers myostatin activity and raises muscle cell growth. The steroidal structure and steroidal backbone of YK-11 set it apart from more traditional SARMs.

Benefits of YK-11 Myostine Capsules United States

Increased Muscle Mass and Strength

YK-11 is often called a SARM, but it is technically a steroidal SARM and myostatin inhibitor. It may increase growth through a unique mechanism of action. By blocking myostatin, a protein that controls muscle growth and differentiation, YK-11 may let muscles grow beyond normal genetic limits.

YK-11 also works as a selective androgen receptor modulator. It activates anabolic pathways in muscle cells to boost protein synthesis and muscle hypertrophy. Animal studies and preclinical research suggest rapid gains in lean muscle mass, greater strength, and higher performance. Some reports mention fewer side effects than anabolic steroids. But studies also report potential side effects such as hair loss, reduced natural testosterone production, the need for liver support, and other negative side effects.

United States Recent research also shows YK-11 may cause oxidative stress and mitochondrial dysfunction across multiple tissues, including the liver and brain.

Improved Bone Health

Protein kinase B (PKB) in cells sends signals that promote bone growth. YK-11 appears to raise these signals. Like other SARMs, YK-11 is under study for bone density support. A study on animal models showed that YK-11 raised bone mineral density and bone strength. This result suggests YK-11 Myostine Capsules may help treat osteoporosis.

Reduced Fatigue

YK-11 Myostine Capsules may also reduce fatigue during activity. In animal models, YK-11 increased the production of follistatin levels. Higher follistatin expression reduces fatigue during exercise and supports faster recovery.

Cognitive Function

Early theoretical studies suggested that androgens may affect cognitive function. YK-11 Myostine Capsules, with their steroidal structure, were first thought to act on androgen receptors like testosterone. Researchers considered this a possible benefit for cognition.

However, newer United States research in animal models shows YK-11 may create cognitive risks. Studies report it causes oxidative stress and mitochondrial dysfunction in the hippocampus. These effects impair memory consolidation. These results suggest possible cognitive harm, though they remain limited to preclinical data and have not yet been confirmed in humans.

Does YK-11 Require Post-Cycle Therapy (PCT)?

YK-11 may affect hormones and natural testosterone production. This raises the chance that post-cycle therapy could be required to restore balance and reduce negative side effects. Reports say some individuals consider PCT important, but controlled human studies have not defined the actual need or best method.

Researchers are also studying YK-11 for its possible role in fat loss and reducing body fat. It may also preserve lean muscle in cases of weakness. These ideas remain limited to animal models.

All reported benefits of YK-11 Myostine Capsules come from animal studies, preclinical research, and anecdotal reports only. No human clinical trials have confirmed its safety or effectiveness.

Like our YK-11 Myostine Capsules? Shop more YK-11 SARM products here from Direct SARMS United States

References:

[1] Yatsu T, Kusakabe T, Kato K, Inouye Y,et al. Selective Androgen Receptor Modulator, YK 11, Up-Regulates Osteoblastic Proliferation and Differentiation in MC3T3-E1 Cells. Biol Pharm Bull. 2018;41(3):394-398.

[2] Lee SJ, Gharbi A, Shin JE, Jung ID, Park YM. Myostatin inhibitor YK 11 as a preventative health supplement for bacterial sepsis. Biochem Biophys Res Commun. 2021 Mar 5;543:1-7. d

[3] Dahleh MMM, Bortolotto VC, Boeira SP, Segat HJ, et al. From gains to gaps? How Selective Androgen Receptor Modulator (SARM) YK 11 impact hippocampal function: In silico, in vivo, and ex vivo perspectives. Chem Biol Interact. 2024 May 1;394:110971.

[4] Dahleh MMM, Bortolotto VC, Guerra GP, Boeira SP, Prigol M. YK 11 induces oxidative stress and mitochondrial dysfunction in hippocampus: The interplay between a selective androgen receptor modulator (SARM) and exercise. J Steroid Biochem Mol Biol. 2023 Oct;233:106364.

[5] Kanno Y, Hikosaka R, Zhang SY, Inoue Y, Nakahama T, Kato K, Yamaguchi A, Tominaga N, Kohra S, Arizono K, Inouye Y. (17α,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK 11) is a partial agonist of the androgen receptor. Biol Pharm Bull. 2011;34(3):318-23.

Molecular Formula: C₂₀H₂₄ClN₃O₄S
Molecular Mass : 437.94026 g/mol

ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our United States Direct Sarms website is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

All images are for display purposes only. The products you receive may differ slightly from the images. But the quality always remands as a premium product.